Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eflumast SCHEMBL1230501 | 0.86 | PKM (0.32) | CYP1A2CYP2C9GPR35RAB9APKM | |
| SCHEMBL10516283 | 0.86 | CYP1A2 (0.37) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL11072324 | 0.85 | CYP1A2 (0.30) | CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL11065854 | 0.84 | — | — | |
| SCHEMBL11074597 | 0.84 | LMNA (0.36) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL10513959 | 0.83 | LMNA (0.32) | LMNAHTT | |
| SCHEMBL11076161 | 0.83 | CYP1A2 (0.36) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL11069754 | 0.82 | CSNK2A1 (0.33) | ALDH1A1 | |
| SCHEMBL10513044 | 0.82 | TTR (0.35) | MEN1KMT2AGPR35 | |
| SCHEMBL11072771 | 0.81 | GPR35 (0.40) | MEN1MAPTKMT2ALMNAGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |