Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eflumast SCHEMBL1230501 | 0.84 | PKM (0.32) | CYP1A2CYP2C9CYP2C19GAACYP3A4 | |
| SCHEMBL10516283 | 0.84 | CYP1A2 (0.37) | CYP1A2CYP2C9CYP2C19HTTTSHR | |
| SCHEMBL11072324 | 0.83 | CYP1A2 (0.30) | CYP1A2CYP2C9CYP2C19GAACYP3A4 | |
| SCHEMBL11067331 | 0.83 | MEN1 (0.35) | CYP1A2CYP2C9HTTKDM4ELMNA | |
| SCHEMBL11074597 | 0.82 | LMNA (0.36) | LMNASMN1; SMN2ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL11065854 | 0.82 | — | — | |
| SCHEMBL10513959 | 0.81 | LMNA (0.32) | HTTLMNAGAA | |
| SCHEMBL11069754 | 0.80 | CSNK2A1 (0.33) | ALDH1A1 | |
| SCHEMBL10513044 | 0.80 | TTR (0.35) | MEN1KMT2AGPR35 | |
| SCHEMBL11073859 | 0.79 | AKR1B1 (0.42) | HTTPOLBLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |