Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.51 |
| ▸ | HTR2A | P28223 | 7/20 | 0.51 |
| ▸ | DRD1 | P21728 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073435 | 0.92 | HTR7 (0.48) | DRD2DRD3HTR7SCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL11070539 | 0.91 | HTR7 (0.47) | DRD2DRD3HTR7SCN1ASCN5A | |
| SCHEMBL11068502 | 0.89 | DRD2 (0.47) | DRD2HTR2ADRD1HTR1ADRD3 | |
| SCHEMBL11065159 | 0.86 | SCN1A (0.49) | DRD2HTR2ADRD1HTR1ADRD3 | |
| SCHEMBL11066472 | 0.85 | DRD2 (0.43) | DRD2HTR2AHTR1ADRD3SCN1A | |
| SCHEMBL11068828 | 0.82 | SCN1A (0.49) | DRD2HTR2AHTR1ADRD3HTR6 | |
| SCHEMBL6108202 | 0.82 | MAOA (0.58) | PARP1MAOAMAOB | |
| SCHEMBL10568577 | 0.81 | DRD2 (0.51) | DRD2HTR2AHTR1ADRD3HTR7 | |
| SCHEMBL11063280 | 0.81 | DRD2 (0.53) | DRD2HTR2ADRD1HTR1ADRD3 | |
| SCHEMBL10572437 | 0.81 | HRH3 (0.49) | DRD2HTR1ADRD3PARP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |