Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065159 | 0.89 | SCN1A (0.49) | SCN1ASCN5ASCN9ADRD2HTR2A | |
| SCHEMBL11073435 | 0.86 | HTR7 (0.48) | SCN1ASCN5ASCN9ADRD2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11070539 | 0.85 | HTR7 (0.47) | SCN1ASCN5ASCN9ADRD2DRD4 | |
| SCHEMBL11066472 | 0.84 | DRD2 (0.43) | SCN1ASCN5ASCN9ADRD2HTR2A | |
| SCHEMBL11070047 | 0.82 | DRD2 (0.51) | SCN1ASCN5ASCN9ADRD2HTR2A | |
| SCHEMBL11068502 | 0.82 | DRD2 (0.47) | DRD2HTR2ADRD4DRD3HTR1A | |
| Iodide SCHEMBL11073338 | 0.81 | ADRB2 (0.39) | SCN1ASCN5ASCN9ADRD2DRD4 | |
| SCHEMBL11065044 | 0.80 | MAOA (0.61) | DRD2DRD4DRD3MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11406538 | 0.80 | DRD2 (0.50) | DRD2DRD4DRD3HTR1AMAOA | |
| SCHEMBL6108202 | 0.80 | MAOA (0.58) | CYP2D6CYP2C19MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |