Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28051044 | 0.92 | CA12 (0.52) | CA12CA7CA14SMN1; SMN2TSHR | |
| Sulfuric Acid SCHEMBL21616458 | 0.92 | CA12 (0.52) | CA12CA7CA14SMN1; SMN2TSHR | |
| Sulfamate SCHEMBL27744770 | 0.88 | CA7 (0.48) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL28051043 | 0.84 | CA12 (0.44) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL3634165 | 0.84 | CA12 (0.44) | CA12CA7CA14SMN1; SMN2TSHR | |
| Sulfuric Acid SCHEMBL2374802 | 0.82 | CA12 (0.43) | CA12CA7CA14SMN1; SMN2TSHR | |
| Sulfuric Acid SCHEMBL7120564 | 0.82 | CA12 (0.43) | CA12CA7CA14SMN1; SMN2TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL10942760 | 0.82 | CA12 (0.43) | CA12CA7CA14SMN1; SMN2TSHR | |
| Methyl Alcohol SCHEMBL28612959 | 0.81 | — | — | |
| Hydrogen Peroxide SCHEMBL11793831 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120022522-A | Drug-loaded microneedle, drug-loaded microneedle patch and electrically-controlled drug release microneedle system | 成都邦迈医创科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-120022522-A | Drug-loaded microneedle, drug-loaded microneedle patch and electrically-controlled drug release microneedle system | 成都邦迈医创科技有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-116848087-A | Process for the preparation of aryl vinyl sulfones | 凯米拉公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-101812039-B | Method for generating 5-hydroxymethylfurfural by using ionic liquid catalysis | UNIV TIANJIN | 2012-09-26 | — | — | CN | disclosed |
| US-20100292469-A1 | PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS | ITALVELLUTI S.P.A. (IT) | 2010-11-18 | — | — | US | disclosed |
| CN-101812039-A | Method for generating 5-hydroxymethylfurfural by using ionic liquid catalysis | UNIV TIANJIN | 2010-08-25 | — | — | CN | disclosed |
| CN-101671316-A | Ion liquid based on morpholine cations and preparation method thereof | DINGZHOU RADI GLORY BIOCHEMICA | 2010-03-17 | — | — | CN | disclosed |
| EP-1794172-B1 | ANTIVIRAL 4'-AZIDO-NUCLEOSIDES | HOFFMANN LA ROCHE (CH) | 2009-07-15 | — | — | EP | disclosed |
| EP-1951691-A1 | PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS | Italvelluti S.p.A. (IT) | 2008-08-06 | — | — | EP | disclosed |
| US-7378402-B2 | 4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; hepatitis C virus. | ROCHE PALO ALTO LLC (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1794172-A1 | ANTIVIRAL 4'-AZIDO-NUCLEOSIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-06-13 | — | — | EP | disclosed |
| WO-2007051496-A1 | PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS | ITALVELLUTI S.P.A. (IT) | 2007-05-10 | — | — | WO | disclosed |
| EP-1644395-B1 | PROCESSES FOR PREPARING 4'AZIDO NUCLEOSIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-11-22 | — | — | EP | disclosed |
| CN-1809582-A | Process for preparing 4' -azido nucleoside derivatives | HOFFMANN LA ROCHE (CH) | 2006-07-26 | — | — | CN | disclosed |
| EP-1644395-A1 | PROCESSES FOR PREPARING 4'AZIDO NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| WO-2006021341-A1 | ANTIVIRAL 4’-AZIDO-NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-02 | — | — | WO | disclosed |
| US-20060040890-A1 | 4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; hepatitis C virus. | ROCHE PALO ALTO LLC | 2006-02-23 | — | — | US | disclosed |
| US-20050038240-A1 | Processes for preparing 4'-azido-nucleoside derivatives | ROCHE PALO ALTO LLC | 2005-02-17 | — | — | US | disclosed |
| WO-2005000864-A1 | PROCESSES FOR PREPARING 4’AZIDO NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038240-A1 | Processes for preparing 4'-azido-nucleoside derivatives | NUDT1, RNGTT, DUT | CA12 3095/4885CA7 1841/4885CA14 3532/4885 |
| US-20060040890-A1 | 4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; hepatitis C virus. | HAVCR2, HCCS, CYP2S1 | CA12 4861/4885CA7 4708/4885CA14 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.