Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | F2R | P25116 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070493 | 1.00 | HDAC11 (0.56) | HDAC11HDAC8NAAASOAT2SOAT1 | |
| SCHEMBL11486775 | 0.89 | NAAA (0.55) | NAAASOAT2SOAT1EPHX2FAAH | |
| SCHEMBL11486773 | 0.89 | NAAA (0.55) | NAAASOAT2SOAT1EPHX2FAAH | |
| SCHEMBL11070282 | 0.88 | SOAT2 (0.52) | HDAC11HDAC8NAAASOAT2SOAT1 | |
| SCHEMBL11070287 | 0.88 | SOAT2 (0.52) | HDAC11HDAC8NAAASOAT2SOAT1 | |
| SCHEMBL11065027 | 0.85 | SOAT2 (0.52) | HDAC11HDAC8SOAT2SOAT1EPHX2 | |
| SCHEMBL11065030 | 0.85 | SOAT2 (0.52) | HDAC11HDAC8SOAT2SOAT1EPHX2 | |
| SCHEMBL11076560 | 0.82 | SOAT2 (0.49) | HDAC11HDAC8SOAT2SOAT1EPHX2 | |
| SCHEMBL11076556 | 0.82 | SOAT2 (0.49) | HDAC11HDAC8SOAT2SOAT1EPHX2 | |
| SCHEMBL11063612 | 0.82 | SOAT2 (0.48) | HDAC11HDAC8SOAT2SOAT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |