Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.56 |
| ▸ | MAOB | P27338 | 10/20 | 0.56 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062872 | 0.88 | KDM1A (0.66) | MAOAMAOBDRD2DRD3HTR1A | |
| SCHEMBL11060298 | 0.82 | SLC2A1 (0.65) | MAOAMAOBDRD2DRD3HTR1A | |
| SCHEMBL11064535 | 0.81 | MAOA (0.64) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11067221 | 0.81 | MAOB (0.79) | MAOAMAOBDRD2DRD3HTR1A | |
| SCHEMBL11066640 | 0.80 | MAOA (0.71) | MAOAMAOBDRD2 | |
| SCHEMBL11066861 | 0.80 | DRD2 (0.69) | MAOAMAOBDRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL11068783 | 0.79 | MAOA (0.70) | MAOAMAOBDRD2 | |
| SCHEMBL23097598 | 0.79 | DRD2 (0.68) | MAOAMAOBDRD2DRD3HTR1A | |
| SCHEMBL10571545 | 0.79 | MAOA (0.86) | MAOAMAOBDRD2DRD3HTR1A | |
| SCHEMBL23097665 | 0.79 | DRD2 (0.63) | MAOAMAOBDRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |