Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 5/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 2/20 | 0.65 |
| ▸ | DRD3 | P35462 | 2/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 11/20 | 0.63 |
| ▸ | MAOB | P27338 | 11/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066640 | 0.92 | MAOA (0.71) | DRD2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11068783 | 0.91 | MAOA (0.70) | DRD2MAOAMAOB | |
| SCHEMBL11060298 | 0.90 | SLC2A1 (0.65) | KDM1ADRD2HTR1AHTR2AHTR2C | |
| SCHEMBL30964249 | 0.89 | MAOA (0.75) | DRD2MAOAMAOB | |
| SCHEMBL11070765 | 0.88 | MAOA (0.56) | KDM1ADRD2HTR1AHTR2AHTR2C | |
| SCHEMBL23097665 | 0.86 | DRD2 (0.63) | DRD2HTR1AHTR2AHTR2CSLC6A4 | |
| SCHEMBL11067221 | 0.86 | MAOB (0.79) | KDM1ADRD2HTR1AHTR2AHTR2C | |
| SCHEMBL11064423 | 0.84 | MAOA (0.56) | KDM1ADRD2HTR1AHTR2AHTR2C | |
| SCHEMBL10571545 | 0.84 | MAOA (0.86) | DRD2HTR1AHTR2AHTR2CSLC6A4 | |
| SCHEMBL23097595 | 0.84 | DRD2 (0.81) | DRD2HTR1AHTR2AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |