Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3248488 | 0.85 | TRPA1 (0.48) | ALDH1A1KMT2ATDP1MEN1ESR1 | |
| SCHEMBL10831575 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1KMT2AMEN1TSHRCACNA1F | |
| SCHEMBL10941810 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL11168208 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KMT2ATDP1MEN1TSHR | |
| SCHEMBL11173454 | 0.73 | TSHR (0.46) | ALDH1A1TDP1ESR1TSHRL3MBTL1 | |
| SCHEMBL6245883 | 0.73 | TRPA1 (0.57) | ALDH1A1TDP1ESR1TSHRL3MBTL1 | |
| SCHEMBL11176919 | 0.73 | AKR1C3 (0.44) | ALDH1A1KMT2AMEN1L3MBTL1PKM | |
| SCHEMBL11165237 | 0.72 | LMNA (0.40) | ALDH1A1KMT2AMEN1TRPA1LMNA | |
| SCHEMBL11172708 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRL3MBTL1TRPA1 | |
| SCHEMBL7734041 | 0.70 | TDP1 (0.58) | ALDH1A1KMT2ATDP1MEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480105-A | PHOTOCROSSLINKING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |