Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641360 | 0.84 | MAPT (0.41) | KMT2AMEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL11069591 | 0.81 | MEN1 (0.39) | KMT2AMEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL10513702 | 0.81 | NPSR1 (0.39) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL11076825 | 0.81 | GABRA1 (0.41) | KMT2AMEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL11072771 | 0.80 | GPR35 (0.40) | KMT2AMEN1HPGDRAB9ANPC1 | |
| SCHEMBL11071748 | 0.78 | IRAK4 (0.37) | KMT2AMEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL11597102 | 0.77 | GSK3B (0.47) | KMT2AMEN1MAPTTSHRMAPK1 | |
| SCHEMBL11067209 | 0.76 | NPC1 (0.51) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL11562864 | 0.74 | KLKB1 (0.53) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4677801 | 0.73 | LMNA (0.52) | KMT2AMEN1ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |