Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.40 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069591 | 0.86 | MEN1 (0.39) | ERN1TP53HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL11071748 | 0.83 | IRAK4 (0.37) | TP53HPGDSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL11067331 | 0.81 | MEN1 (0.35) | GPR35HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL11070877 | 0.80 | KMT2A (0.41) | HPGDSMN1; SMN2L3MBTL1MAPTNPC1 | |
| SCHEMBL11076161 | 0.75 | CYP1A2 (0.36) | GPR35TP53HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL11597102 | 0.72 | GSK3B (0.47) | SMN1; SMN2MAPTPOLBKDM4EMEN1 | |
| Eflumast SCHEMBL1230501 | 0.70 | PKM (0.32) | GPR35NPC1RAB9AGAA | |
| SCHEMBL10516283 | 0.70 | CYP1A2 (0.37) | TP53HPGDMAPTLMNANPC1 | |
| SCHEMBL11072324 | 0.69 | CYP1A2 (0.30) | GAA | |
| Hydrochloric Acid SCHEMBL11065854 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |