Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TFEB | P19484 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19076160 | 0.86 | NPC1 (0.74) | KDM4ERAB9ANPC1MAPTGAA | |
| SCHEMBL28249887 | 0.83 | KDM4E (0.57) | KDM4ERAB9ANPC1MAPTGAA | |
| SCHEMBL240090 | 0.78 | CA1 (0.60) | KDM4ERAB9ANPC1MAPTMAPK1 | |
| SCHEMBL3818033 | 0.76 | NPC1 (0.52) | KDM4ERAB9ANPC1MAPTGAA | |
| SCHEMBL10483258 | 0.74 | NPC1 (0.50) | KDM4ERAB9ANPC1MAPTGAA | |
| SCHEMBL41190 | 0.73 | RAB9A (0.74) | KDM4ERAB9ANPC1MAPK1KMT2A | |
| SCHEMBL19076184 | 0.73 | NFE2L2 (0.59) | KDM4ERAB9ANPC1MAPTGAA | |
| SCHEMBL28347777 | 0.73 | NFE2L2 (0.59) | KDM4ERAB9ANPC1MAPTGAA | |
| SCHEMBL14401506 | 0.72 | MAPT (0.61) | KDM4ERAB9ANPC1MAPTGAA | |
| SCHEMBL16098068 | 0.71 | NR4A1 (0.54) | KDM4ERAB9ANPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426521-A | LOCAL ANESTHETIC, ANTISECRETORY, DIURETIC, ANTIDEPRESSANT | EISAI CO., LTD. (JP) | 1984-01-17 | — | — | US | disclosed |