Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19076160 | 0.83 | NPC1 (0.74) | MAPTKDM4ENPC1RAB9AGAA | |
| SCHEMBL8854378 | 0.79 | CYP1A1 (0.65) | MAPTNPC1RAB9AGAACYP1A1 | |
| SCHEMBL22010235 | 0.79 | CYP1A1 (0.65) | MAPTNPC1RAB9AGAACYP1A1 | |
| SCHEMBL9189623 | 0.75 | TUBB4A (0.65) | MAPTKDM4ENPC1RAB9AGAA | |
| SCHEMBL21005800 | 0.75 | TUBB4A (0.65) | MAPTKDM4ENPC1RAB9AGAA | |
| SCHEMBL9189630 | 0.75 | TUBB4A (0.65) | MAPTKDM4ENPC1RAB9AGAA | |
| SCHEMBL10385902 | 0.74 | PTGS1 (0.65) | MAPTKDM4ENPC1RAB9AGAA | |
| Bromide SCHEMBL28082033 | 0.74 | TUBB4A (0.63) | MAPTKDM4ENPC1RAB9AGAA | |
| SCHEMBL29256842 | 0.74 | NPC1 (0.48) | MAPTKDM4ENPC1RAB9AGAA | |
| Methyl Alcohol SCHEMBL28478479 | 0.73 | NPC1 (0.89) | MAPTKDM4ENPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110540-A2 | DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING AN ALKOXY/HYDROXY GROUPING, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |