Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | TFEB | P19484 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070944 | 0.86 | KDM4E (0.60) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL19076184 | 0.84 | NFE2L2 (0.59) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL28347777 | 0.84 | NFE2L2 (0.59) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL16915478 | 0.83 | RAB9A (0.55) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL16915477 | 0.83 | RAB9A (0.55) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL28249887 | 0.83 | KDM4E (0.57) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL14401506 | 0.83 | MAPT (0.61) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL4019329 | 0.82 | NFE2L2 (0.79) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL1603719 | 0.82 | NFE2L2 (0.79) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL7915752 | 0.82 | NFE2L2 (0.79) | NPC1RAB9AKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041904-B1 | STYRYL SULFIDE DYES | BASF SE (DE) | 2020-05-20 | — | — | EP | disclosed |
| US-20170189566-A1 | ALPHA-SYNUCLEIN LIGANDS | WASHINGTON UNIVERSITY (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189566-A1 | ALPHA-SYNUCLEIN LIGANDS | SNCA, PARK7, LRRK2 | NPC1 382/4885RAB9A 152/4885KDM4E 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.