Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542322 | 0.83 | TAAR1 (0.46) | TAAR1FFAR4HRH3THRATHRB | |
| SCHEMBL1921167 | 0.82 | CTBP2 (0.50) | TAAR1FFAR4THRATHRBCTBP2 | |
| SCHEMBL456436 | 0.81 | FFAR4 (0.67) | TAAR1FFAR4THRATHRBCTBP2 | |
| SCHEMBL21707533 | 0.80 | TAAR1 (0.50) | TAAR1FFAR4HRH3IDO1DAO | |
| SCHEMBL12802159 | 0.80 | TAAR1 (0.50) | TAAR1FFAR4HRH3THRATHRB | |
| SCHEMBL8096473 | 0.79 | TAAR1 (0.74) | TAAR1HRH3IDO1DAOGPR84 | |
| SCHEMBL29596752 | 0.79 | TAAR1 (0.74) | TAAR1HRH3IDO1DAOGPR84 | |
| SCHEMBL13176544 | 0.78 | DRD2 (0.57) | TAAR1IDO1HDAC6 | |
| SCHEMBL7337631 | 0.78 | TAAR1 (0.57) | TAAR1FFAR4THRATHRBDAO | |
| SCHEMBL16542359 | 0.78 | TAAR1 (0.47) | TAAR1FFAR4HRH3THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153660-B2 | Piperidyl-propane-thiol CCR3 modulators | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-10 | — | — | US | disclosed |