Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107169 | 0.80 | TAAR1 (0.55) | TAAR1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL16429377 | 0.80 | ALDH1A1 (0.50) | TAAR1HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL14724832 | 0.79 | MEN1 (0.53) | TAAR1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL24409529 | 0.79 | HPGD (0.36) | HDAC1FFAR4CNR1HPGD | |
| SCHEMBL12802159 | 0.76 | TAAR1 (0.50) | TAAR1HDAC3HDAC1HDAC2HDAC10 | |
| Dimethylamine SCHEMBL9871069 | 0.76 | FFAR4 (0.62) | TAAR1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1921167 | 0.75 | CTBP2 (0.50) | TAAR1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29596752 | 0.74 | TAAR1 (0.74) | TAAR1HRH3DAOIDO1NR3C2 | |
| SCHEMBL8096473 | 0.74 | TAAR1 (0.74) | TAAR1HRH3DAOIDO1NR3C2 | |
| SCHEMBL20906984 | 0.74 | RAB9A (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033521-A1 | CROSS-LINKED RADIOPAQUE BIORESORBABLE POLYMERS AND DEVICES MADE THEREFROM | REVA MEDICAL, INC. (US) | 2020-02-13 | — | — | WO | disclosed |