Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679742 | 0.90 | NPC1 (0.52) | CTBP2FFAR4TAAR1THRATHRB | |
| SCHEMBL17940821 | 0.83 | FFAR1 (0.55) | FFAR4FFAR1TDP1L3MBTL1 | |
| SCHEMBL7440906 | 0.83 | CTBP2 (0.61) | CTBP2TAAR1ALDH1A1KDM4ECASP3 | |
| SCHEMBL17975817 | 0.83 | FFAR1 (0.53) | ALDH1A1FFAR1HDAC3HDAC1HDAC2 | |
| SCHEMBL28167994 | 0.83 | FFAR4 (0.47) | FFAR4TAAR1THRATHRBALDH1A1 | |
| SCHEMBL456436 | 0.82 | FFAR4 (0.67) | CTBP2FFAR4TAAR1THRATHRB | |
| SCHEMBL1107169 | 0.82 | TAAR1 (0.55) | CTBP2FFAR4TAAR1THRATHRB | |
| SCHEMBL1137422 | 0.81 | DRD2 (0.50) | CTBP2TAAR1FFAR1HDAC6 | |
| SCHEMBL7337631 | 0.80 | TAAR1 (0.57) | CTBP2FFAR4TAAR1THRATHRB | |
| SCHEMBL1919956 | 0.80 | PLAAT3 (0.54) | CTBP2FFAR4TAAR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | claimed |
| EP-3200840-B1 | LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC (CH) | 2021-11-17 | — | — | EP | claimed |
| EP-3200839-B1 | HYDROPHOBIC ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | NOVARTIS AG (CH) | 2019-09-04 | — | — | EP | claimed |
| EP-3223870-B1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | NOVARTIS AG (CH) | 2018-09-26 | — | — | EP | claimed |
| EP-3077016-B1 | SOFT ACRYLIC MATERIALS WITH HIGH REFRACTIVE INDEX AND MINIMIZED GLISTENING | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | claimed |
| EP-2292672-B1 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | CIS PHARMA AG (CH) | 2018-05-09 | — | — | EP | claimed |
| EP-1888660-B1 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CIS PHARMA AG (CH) | 2017-05-17 | — | — | EP | claimed |
| EP-2906970-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS WITH REDUCED TACK | NOVARTIS AG (CH) | 2016-11-23 | — | — | EP | claimed |
| EP-2582409-B1 | HIGH REFRACTIVE INDEX, ACRYLIC OPHTHALMIC DEVICE MATERIALS WITH REDUCED GLISTENINGS | NOVARTIS AG (CH) | 2014-09-10 | — | — | EP | claimed |
| EP-2225325-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON INC (CH) | 2011-06-01 | — | — | EP | claimed |
| EP-1080382-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON INC (CH) | 2009-07-08 | — | — | EP | claimed |
| EP-1080381-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS PREPARED USING A POST-POLYMERIZATION CROSS-LINKING METHOD | ALCON MFG LTD (US) | 2005-07-27 | — | — | EP | claimed |
| EP-1002244-B1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LAB INC (US) | 2003-02-26 | — | — | EP | claimed |
| EP-1079870-B1 | BICOMPOSITE INTRAOCULAR LENS AND METHOD FOR ITS PREPARATION | ALCON LAB INC (US) | 2001-11-14 | — | — | EP | claimed |
| EP-1071482-B1 | INTRAOCULAR LENS COATING COMPOSITIONS | ALCON LAB INC (US) | 2001-10-04 | — | — | EP | claimed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20140242722-A1 | ARTICLE AND METHOD FOR DETECTION OF A DRUG IN A LIQUID MEDIUM | MEDTECH DETECT, LLC (US) | 2014-08-28 | — | — | US | disclosed |
| US-20070172772-A1 | Microlens | OMRON CORPORATION (JP) | 2007-07-26 | — | — | US | disclosed |