Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11073162 | 0.99 | ADRB2 (0.56) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| SCHEMBL8068855 | 0.85 | KDM4E (0.59) | ADRB2ADRB1KDM4EADRB3SMN1; SMN2 | |
| SCHEMBL10563518 | 0.84 | ADRB2 (0.56) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| SCHEMBL10563514 | 0.84 | ADRB2 (0.56) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| SCHEMBL11071851 | 0.84 | ADRB1 (0.65) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| SCHEMBL11078899 | 0.83 | MEN1 (0.70) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL11480654 | 0.79 | ADRB2 (0.68) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL11480657 | 0.79 | ADRB2 (0.68) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| SCHEMBL10892246 | 0.78 | ADRB2 (0.68) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D | |
| SCHEMBL11465017 | 0.78 | ADRB2 (0.60) | ADRB2ADRB1ALDH1A1ADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450115-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AND CARDIOTONIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| US-4450115-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AND CARDIOTONIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
| US-4381398-A | Amino-alcohol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-04-26 | — | — | US | disclosed |