Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045605 | 0.97 | OPRM1 (0.50) | OPRM1OPRL1KDM1ASIGMAR1ALOX5 | |
| SCHEMBL30404322 | 0.97 | OPRM1 (0.50) | OPRM1OPRL1KDM1ASIGMAR1ALOX5 | |
| Ethylene SCHEMBL11097079 | 0.81 | KDM1A (0.47) | OPRM1OPRL1KDM1ASIGMAR1ALOX5 | |
| SCHEMBL11081467 | 0.81 | OPRM1 (0.50) | OPRM1OPRL1KDM1ASIGMAR1ALOX5 | |
| Ethylene SCHEMBL11096905 | 0.81 | OPRL1 (0.45) | OPRM1OPRL1OPRD1OPRK1KMT2A | |
| SCHEMBL11070774 | 0.81 | CYP3A4 (0.45) | OPRM1OPRL1ALOX5KMT2AMEN1 | |
| SCHEMBL22538479 | 0.80 | OPRM1 (0.54) | OPRM1OPRL1KDM1ASLC6A2SLC6A4 | |
| SCHEMBL11093745 | 0.80 | ALOX5 (0.44) | OPRM1OPRL1ALOX5SLC6A2SLC6A4 | |
| Ethylene SCHEMBL10832290 | 0.79 | OPRD1 (0.41) | OPRM1OPRL1SIGMAR1SLC6A2SLC6A4 | |
| Ethylene SCHEMBL11079878 | 0.79 | HDAC3 (0.43) | OPRM1OPRL1KDM1ASIGMAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |