Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613824 | 0.97 | KDM1A (0.49) | KDM1ASIGMAR1ALOX5HSD11B1KMT2A | |
| SCHEMBL3159689 | 0.84 | KDM1A (0.57) | KDM1AOPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL18742400 | 0.82 | KDM1A (0.56) | KDM1AOPRM1OPRD1OPRK1OPRL1 | |
| Ethylene SCHEMBL11072035 | 0.81 | OPRM1 (0.48) | KDM1ASIGMAR1ALOX5OPRM1OPRD1 | |
| SCHEMBL8003754 | 0.81 | ALOX5 (0.46) | ALOX5KMT2ABACE1ALDH1A1 | |
| SCHEMBL17982834 | 0.81 | KDM1A (0.54) | KDM1ASLC6A4 | |
| SCHEMBL521519 | 0.81 | KDM1A (0.54) | KDM1AKMT2ASLC6A4 | |
| Ethylene SCHEMBL11079878 | 0.80 | HDAC3 (0.43) | KDM1ASIGMAR1ALOX5OPRM1OPRD1 | |
| SCHEMBL20917407 | 0.80 | SIGMAR1 (0.45) | KDM1ASIGMAR1BACE1CTSDCTSE | |
| Hydrochloric Acid SCHEMBL18742809 | 0.80 | KDM1A (0.53) | KDM1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |