Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707476 | 0.83 | TP53 (0.48) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10032038 | 0.83 | TP53 (0.51) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11329170 | 0.82 | TP53 (0.47) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11066821 | 0.80 | MEN1 (0.51) | NMT1TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL6200817 | 0.79 | NR3C1 (0.49) | MEN1KMT2ALMNANPSR1EGLN1 | |
| Alcohol SCHEMBL11089265 | 0.78 | NMT1 (0.46) | NMT1TP53MEN1KMT2AMAPT | |
| SCHEMBL10971509 | 0.77 | RAB9A (0.48) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8537994 | 0.77 | TP53 (0.51) | TP53MAPT | |
| Hydrochloric Acid SCHEMBL11065517 | 0.77 | RAB9A (0.48) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL397958 | 0.75 | MAOA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450166-A | N-(4,5-Dihydro-thiazol-2-yl)-3-quinoline-carboxamides having anxiolytic activity | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |