Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077944 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL11071937 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL11077939 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL9380094 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL6266846 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL11074157 | 0.67 | KMT2A (0.57) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL8199613 | 0.67 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL31262945 | 0.67 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| 4,6,7-Trimethyl-2H-Chromen-2-One SCHEMBL19049403 | 0.66 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL1002900 | 0.66 | ALDH1A1 (1.00) | KDM4EALDH1A1HSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |