Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559080 | 0.82 | POLB (0.59) | KDM4EALDH1A1AKR1B1THRBUSP2 | |
| SCHEMBL11077944 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL5085548 | 0.77 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDMCL1AKR1B1 | |
| SCHEMBL31081384 | 0.77 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDMCL1AKR1B1 | |
| SCHEMBL11098611 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL11743352 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL5563883 | 0.74 | AKR1B1 (0.65) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL11072186 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL5084426 | 0.73 | AKR1B1 (0.69) | KDM4EALDH1A1HPGDAKR1B1THRB | |
| SCHEMBL379054 | 0.73 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDHSD17B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | claimed |
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |