Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | GLA | P06280 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072186 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL11077939 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL11098613 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6036796 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11066772 | 0.74 | LMNA (0.41) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL11071978 | 0.72 | GAA (0.54) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL7455688 | 0.71 | AKR1B1 (0.60) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL1865302 | 0.70 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL1864108 | 0.70 | KDM4E (0.58) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL5220493 | 0.70 | GABRP (0.52) | MAPTCASP1SMN1; SMN2CYP3A4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | claimed |
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |