Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11855298 | 1.00 | ACHE (0.53) | ACHEBACE1CA2MAPK1HCAR2 | |
| SCHEMBL5501041 | 0.92 | GPR84 (0.50) | ACHEBACE1HCAR2GPR84FFAR1 | |
| SCHEMBL8357531 | 0.82 | ACHE (0.47) | ACHEBACE1CA2MAPK1HCAR2 | |
| SCHEMBL16468632 | 0.82 | ACHE (0.47) | ACHEBACE1CA2MAPK1HCAR2 | |
| SCHEMBL2963668 | 0.82 | CA2 (0.47) | ACHEBACE1CA2MAPK1GPR84 | |
| SCHEMBL8488815 | 0.82 | CA2 (0.47) | ACHEBACE1CA2MAPK1GPR84 | |
| SCHEMBL1474367 | 0.82 | CA2 (0.47) | ACHEBACE1CA2MAPK1GPR84 | |
| SCHEMBL19326808 | 0.81 | GABRP (0.41) | ACHEBACE1GPR84FFAR1GABRP | |
| SCHEMBL1129486 | 0.80 | CA2 (0.45) | ACHEBACE1CA2MAPK1GPR84 | |
| SCHEMBL1129485 | 0.80 | CA2 (0.45) | ACHEBACE1CA2MAPK1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31522-E | COPOLYMERS OF DIAMINE-ENDCAPPED POLYOXYETHYLENE GLYCOLS AND A DICARBOXYLIC ACID; HYDRAULIC FLUIDS; METAL WORKING | CINCINNATI MILACRON INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4374741-A | LUBRICANTS, METAL WORKING, POLYETHER BLOCK POLYMERJ | CINCINNATI MILACRON INC. (US) | 1983-02-22 | — | — | US | disclosed |
| US-3983230-A | HALF ESTERS WITH DICARBOXYLIC ACIDS, MEDICAMENTS | SHIONOGI & CO., LTD. (JA) | 1976-09-28 | — | — | US | disclosed |