Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079424 | 0.83 | LMNA (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11080788 | 0.80 | LMNA (0.49) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL19110998 | 0.76 | BCHE (0.62) | BCHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13233335 | 0.76 | BCHE (0.62) | BCHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8940750 | 0.75 | ROCK2 (0.44) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL8277405 | 0.74 | BCHE (0.68) | BCHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16353729 | 0.74 | BCHE (1.00) | BCHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11923469 | 0.74 | HDAC3 (0.62) | BCHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2605750 | 0.73 | BCHE (0.53) | BCHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14752365 | 0.73 | BCHE (0.53) | BCHEHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |