Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072591 | 0.83 | BCHE (0.58) | LMNASMN1; SMN2POLBHDAC3HDAC4 | |
| SCHEMBL11078900 | 0.82 | NPC1 (0.60) | LMNASMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL11072102 | 0.80 | ALDH1A1 (0.63) | LMNASMN1; SMN2POLBPKMMEN1 | |
| SCHEMBL11072104 | 0.80 | ALDH1A1 (0.63) | LMNASMN1; SMN2POLBPKMMEN1 | |
| SCHEMBL19111004 | 0.79 | EPHX2 (0.70) | LMNASMN1; SMN2POLBEPHX2HDAC3 | |
| SCHEMBL19176792 | 0.79 | LMNA (0.63) | LMNASMN1; SMN2POLBEPHX2HDAC3 | |
| SCHEMBL11073535 | 0.78 | TSHR (0.60) | LMNASMN1; SMN2POLBPKMMAPK1 | |
| SCHEMBL10447927 | 0.78 | FFAR2 (0.47) | LMNASMN1; SMN2NOTUMPKMKMT2A | |
| SCHEMBL9456935 | 0.78 | ABCC9 (0.57) | PKMKMT2A | |
| SCHEMBL5356584 | 0.77 | SMN1; SMN2 (0.73) | LMNASMN1; SMN2POLBEPHX2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |