Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072243 | 0.90 | OPRL1 (0.33) | OPRM1OPRL1CRHR1 | |
| SCHEMBL11077431 | 0.86 | OPRM1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL11076219 | 0.84 | L3MBTL1 (0.36) | SLC6A4SLC6A3CRHR1 | |
| SCHEMBL11073495 | 0.80 | PGR (0.33) | — | |
| SCHEMBL11074662 | 0.79 | SLC6A4 (0.32) | DRD2DRD3SLC6A4SLC6A3 | |
| SCHEMBL11077880 | 0.79 | OPRM1 (0.39) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL11078604 | 0.77 | SLC6A4 (0.32) | DRD2DRD3SLC6A4SLC6A3 | |
| SCHEMBL11075816 | 0.77 | HTR2A (0.31) | OPRM1OPRL1 | |
| SCHEMBL11069896 | 0.77 | OPRM1 (0.43) | OPRM1OPRL1TSPO | |
| SCHEMBL11079381 | 0.76 | PGR (0.31) | OPRM1OPRL1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |