Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31107080 | 0.80 | LMNA (0.54) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| SCHEMBL974064 | 0.80 | LMNA (0.54) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| SCHEMBL974062 | 0.80 | LMNA (0.54) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| SCHEMBL11349953 | 0.80 | LMNA (0.54) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| SCHEMBL7522058 | 0.78 | LMNA (0.52) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| Water SCHEMBL7529368 | 0.78 | LMNA (0.52) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| SCHEMBL8103071 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL7523599 | 0.78 | LMNA (0.52) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| SCHEMBL7522924 | 0.78 | LMNA (0.52) | GABRA1GABRB2TSHRHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL1375900 | 0.78 | LMNA (0.52) | GABRA1GABRB2TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034443-B1 | BETA-LACTAM ANTIBACTERIAL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |