Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.64 |
| ▸ | DRD3 | P35462 | 6/20 | 0.64 |
| ▸ | DRD4 | P21917 | 5/20 | 0.64 |
| ▸ | MAOA | P21397 | 11/20 | 0.64 |
| ▸ | MAOB | P27338 | 11/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062991 | 0.91 | DRD2 (0.64) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11064535 | 0.87 | MAOA (0.64) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11074474 | 0.87 | MAOA (0.68) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11070978 | 0.85 | DRD2 (0.71) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11063294 | 0.85 | DRD2 (0.68) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11066832 | 0.85 | MAOA (0.68) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11066640 | 0.85 | MAOA (0.71) | DRD2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11068783 | 0.84 | MAOA (0.70) | DRD2MAOAMAOB | |
| SCHEMBL10572465 | 0.83 | DRD2 (0.74) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11066861 | 0.83 | DRD2 (0.69) | DRD2DRD3DRD4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |