Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.68 |
| ▸ | MAOA | P21397 | 15/20 | 0.66 |
| ▸ | MAOB | P27338 | 14/20 | 0.66 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | HTR3B | O95264 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066861 | 0.88 | DRD2 (0.69) | DRD2MAOAMAOBHTR3EMEN1 | |
| SCHEMBL11074474 | 0.87 | MAOA (0.68) | DRD2MAOAMAOBDRD4DRD3 | |
| SCHEMBL11066832 | 0.87 | MAOA (0.68) | DRD2MAOAMAOBHTR1ADRD1 | |
| SCHEMBL11066640 | 0.86 | MAOA (0.71) | DRD2MAOAMAOBHTR6 | |
| Hydrochloric Acid SCHEMBL11068783 | 0.85 | MAOA (0.70) | DRD2MAOAMAOBHTR6 | |
| SCHEMBL11073618 | 0.85 | DRD2 (0.64) | DRD2MAOAMAOBDRD4DRD3 | |
| SCHEMBL11071264 | 0.85 | DRD2 (0.82) | DRD2MAOAMAOBHTR3EMEN1 | |
| SCHEMBL30964249 | 0.83 | MAOA (0.75) | DRD2MAOAMAOBHTR6 | |
| SCHEMBL11064535 | 0.83 | MAOA (0.64) | DRD2MAOAMAOBDRD4DRD3 | |
| SCHEMBL11060298 | 0.83 | SLC2A1 (0.65) | DRD2MAOAMAOBHTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |