Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516283 | 0.89 | CYP1A2 (0.37) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11072501 | 0.84 | ALDH1A1 (0.36) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11065956 | 0.83 | CYP1A2 (0.35) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11071199 | 0.83 | MEN1 (0.35) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11073948 | 0.83 | CXCR2 (0.37) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11070064 | 0.82 | CYP1A2 (0.34) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11072576 | 0.81 | ACR (0.38) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL11063432 | 0.81 | ALDH1A1 (0.34) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11069591 | 0.78 | MEN1 (0.39) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| Eflumast SCHEMBL1230501 | 0.77 | PKM (0.32) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |