Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065956 | 0.91 | CYP1A2 (0.35) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL10516283 | 0.84 | CYP1A2 (0.37) | ALDH1A1HPGDTSHRHSD17B10CYP1A2 | |
| SCHEMBL11072576 | 0.84 | ACR (0.38) | ALDH1A1HPGDALOX15TSHRHSD17B10 | |
| SCHEMBL11070756 | 0.83 | GAA (0.42) | ALDH1A1HPGDTSHRHSD17B10CYP1A2 | |
| SCHEMBL11072501 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL11071199 | 0.81 | MEN1 (0.35) | ALDH1A1TDP1CYP1A2CYP3A4APOBEC3A | |
| SCHEMBL11073867 | 0.81 | CYP1A2 (0.35) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11073948 | 0.81 | CXCR2 (0.37) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11070064 | 0.81 | CYP1A2 (0.34) | CYP1A2CYP3A4APOBEC3ACYP2C19APOBEC3G | |
| SCHEMBL11064670 | 0.78 | LMNA (0.31) | ALDH1A1HPGDMAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |