Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848331 | 0.68 | CYP3A4 (0.40) | CYP2D6ALDH1A1SMN1; SMN2TSHRRAB9A | |
| SCHEMBL11076541 | 0.68 | GAA (0.39) | GAACYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11771789 | 0.66 | MAPT (0.46) | GAAALDH1A1MAPTUSP2ALOX15 | |
| SCHEMBL8521517 | 0.66 | TSHR (0.42) | GAACYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL37520 | 0.65 | MAPT (0.56) | GAACYP2D6ALDH1A1MAPTTSHR | |
| SCHEMBL7307659 | 0.65 | L3MBTL1 (0.40) | GAACYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8848434 | 0.65 | CHRNB2 (0.40) | GAACYP2D6ALDH1A1MAPTCHRNA7 | |
| SCHEMBL8848447 | 0.65 | CHRNB2 (0.40) | GAACYP2D6ALDH1A1MAPTCHRNA7 | |
| SCHEMBL8848438 | 0.65 | CHRNB2 (0.40) | GAACYP2D6ALDH1A1MAPTCHRNA7 | |
| SCHEMBL10025073 | 0.65 | MAPT (0.46) | ALDH1A1MAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026369-B1 | CARBAMATES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1984-08-08 | — | — | EP | disclosed |
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |