Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309011 | 0.81 | TSHR (0.39) | CYP3A4ALDH1A1MAPK1CYP2D6USP2 | |
| SCHEMBL8521517 | 0.76 | TSHR (0.42) | CYP3A4ALDH1A1MAPK1CYP2D6USP2 | |
| SCHEMBL10025073 | 0.75 | MAPT (0.46) | ALDH1A1USP2KDM4EHPGD | |
| SCHEMBL8646552 | 0.75 | THRB (0.47) | ALDH1A1TSHRSMN1; SMN2KDM4ERAB9A | |
| Cyclohexane SCHEMBL23214149 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4EFAAHRAB9A | |
| SCHEMBL10025075 | 0.74 | MAPT (0.44) | ALDH1A1USP2KDM4EHPGD | |
| SCHEMBL322125 | 0.74 | MAPT (0.44) | ALDH1A1USP2KDM4EHPGD | |
| SCHEMBL6895096 | 0.74 | MAPT (0.44) | ALDH1A1USP2KDM4EHPGD | |
| SCHEMBL8888100 | 0.72 | KDM4E (0.41) | CYP3A4ALDH1A1MAPK1USP2TSHR | |
| SCHEMBL7307659 | 0.72 | L3MBTL1 (0.40) | CYP3A4ALDH1A1MAPK1CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |