Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848447 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNA5CHRNA7CHRNA4ABCB1 | |
| SCHEMBL8848438 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNA5CHRNA7CHRNA4ABCB1 | |
| SCHEMBL8522579 | 0.84 | CHRNB2 (0.42) | CHRNB2CHRNA5CHRNA7CHRNA4ABCB1 | |
| SCHEMBL8522102 | 0.79 | CYP2D6 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL8522099 | 0.79 | CYP2D6 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL8522094 | 0.79 | CYP2D6 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL8309536 | 0.74 | SMN1; SMN2 (0.38) | GAAALDH1A1MAPTATML3MBTL1 | |
| SCHEMBL8308800 | 0.74 | SMN1; SMN2 (0.38) | GAAALDH1A1MAPTATML3MBTL1 | |
| SCHEMBL8308796 | 0.74 | SMN1; SMN2 (0.38) | GAAALDH1A1MAPTATML3MBTL1 | |
| SCHEMBL8308799 | 0.74 | SMN1; SMN2 (0.38) | GAAALDH1A1MAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |