Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 13/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849339 | 1.00 | KDM4E (0.51) | KDM4EKCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL10849342 | 0.80 | KDM4E (0.56) | KDM4EKCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL10846473 | 0.80 | KCNE1 (0.34) | KCNE1KCNQ1CYP3A4MEN1CYP1A2 | |
| SCHEMBL11085099 | 0.80 | KCNE1 (0.34) | KCNE1KCNQ1CYP3A4MEN1CYP1A2 | |
| SCHEMBL10848288 | 0.80 | KCNE1 (0.36) | KDM4EKCNE1KCNQ1 | |
| SCHEMBL11072866 | 0.80 | KCNE1 (0.36) | KDM4EKCNE1KCNQ1 | |
| SCHEMBL10849336 | 0.80 | KDM4E (0.56) | KDM4EKCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL10847995 | 0.79 | ABCC9 (0.50) | ABCB1ABCC9 | |
| SCHEMBL10853875 | 0.79 | ABCC9 (0.50) | ABCB1ABCC9 | |
| SCHEMBL10853889 | 0.79 | ABCC9 (0.50) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126350-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1984-11-28 | — | — | EP | claimed |