Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 4/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072866 | 1.00 | KCNE1 (0.36) | KCNE1KCNQ1KDM4E | |
| SCHEMBL10848293 | 0.82 | KDM4E (0.38) | KCNE1KCNQ1KDM4E | |
| SCHEMBL10848280 | 0.82 | KDM4E (0.38) | KCNE1KCNQ1KDM4E | |
| SCHEMBL11074219 | 0.80 | KDM4E (0.51) | KCNE1KCNQ1KDM4E | |
| SCHEMBL10846473 | 0.80 | KCNE1 (0.34) | KCNE1KCNQ1 | |
| SCHEMBL10849339 | 0.80 | KDM4E (0.51) | KCNE1KCNQ1KDM4E | |
| SCHEMBL11085099 | 0.80 | KCNE1 (0.34) | KCNE1KCNQ1 | |
| SCHEMBL10851959 | 0.79 | ABCC9 (0.38) | — | |
| SCHEMBL11081340 | 0.72 | ABCC9 (0.51) | KDM4E | |
| SCHEMBL10852188 | 0.72 | ABCC9 (0.51) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4629734-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1986-12-16 | — | — | US | claimed |
| EP-0126350-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1984-11-28 | — | — | EP | claimed |
| US-4629734-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1986-12-16 | — | — | US | disclosed |
| EP-0126350-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1984-11-28 | — | — | EP | disclosed |