SCHEMBL11074497

SCHEMBL11074497

Oc1ccccc1C1=CC=CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 2/20 0.41
BCL2L1 Q07817 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 3/20 0.36
KDM4E B2RXH2 2/20 0.36
RECQL P46063 2/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36
GMNN O75496 1/20 0.36
EGFR P00533 1/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 1/20 0.36
FYN P06241 1/20 0.36
POLB P06746 1/20 0.36
CA3 P07451 1/20 0.36
CYP3A4 P08684 1/20 0.36
MMP9 P14780 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27738150 0.98 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Biphenyl SCHEMBL27502002 0.93 HPGD (0.50) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Biphenyl SCHEMBL27708316 0.86 HPGD (0.47) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL30626777 0.84
SCHEMBL28006187 0.84
SCHEMBL10495969 0.82 MAOA (0.39) ALDH1A1HPGDHSD17B10SMN1; SMN2MAPT
SCHEMBL28856005 0.82 HSD17B10 (0.40) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL27365125 0.80 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL29938717 0.80 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL21044936 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322278-B Sulfonated nitrostyrene resin and preparation method and application thereof 杭摩科技新材料(阜阳)有限公司 2024-06-07 CN claimed
CN-115322278-B Sulfonated nitrostyrene resin and preparation method and application thereof 杭摩科技新材料(阜阳)有限公司 2024-06-07 CN disclosed
CN-117417518-A Hyperbranched active ester polymer and preparation method and application thereof 北京化工大学 2024-01-19 CN disclosed
CN-116410223-A Tetraarylethoxy side chain single metallocene compound, catalyst system containing same and polyolefin synthesis method using same 中国石油天然气股份有限公司 2023-07-11 CN disclosed
WO-2023123884-A1 TETRAARYL ETHOXY SIDE-CHAIN MONO-METALLOCENE COMPOUND, CATALYST SYSTEM COMPRISING SAME, AND POLYOLEFIN SYNTHESIS METHOD USING SAME 中国石油天然气股份有限公司 2023-07-06 WO disclosed
US-8252561-B2 Production of biofuel using molluscan pseudofeces derived from algal cells UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-08-28 US disclosed
US-20110105554-A1 MEANS FOR TREATING MYOSIN-RELATED DISEASES KINARIS BIOMEDICALS GMBH (DE) 2011-05-05 US disclosed
CN-100506768-C 2,4-di-(1-phenylisopropyl) phenol preparation method CHINA PETROLEUM & CHEMICAL (CN) 2009-07-01 CN disclosed
CN-100491315-C Process for preparing 2,4-dicumyl phenol CHINA PETROLEUM & CHEMICAL (CN) 2009-05-27 CN disclosed
CN-1962591-A 2,4-di-(1-phenylisopropyl) phenol preparation method CHINA PETROLEUM & CHEMICAL (CN) 2007-05-16 CN disclosed
CN-1884245-A Process for preparing 2,4-dicumyl phenol CHINA PETROLEUM & CHEMICAL (CN) 2006-12-27 CN disclosed
CN-1034547-A CATALYST FOR POLYMERIZATION OF ALPHA-OLEFINE AND POLYMERIZATION PROCESS MITSUI PETROCHEMICAL IND (JP) 1989-08-09 CN disclosed
US-4484010-A POLYMER ANTIOXIDANT THE B. F. GOODRICH COMPANY (US) 1984-11-20 US disclosed
EP-0113666-A1 Hydroxybenzylcyclopentadienes and derivatives thereof The B.F. GOODRICH Company (US) 1984-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105554-A1 MEANS FOR TREATING MYOSIN-RELATED DISEASES MYH14, MYH2, MYLK2 ALDH1A1 4152/4885HPGD 2787/4885HSD17B10 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.