Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18284609 | 0.84 | PPARG (0.40) | SMN1; SMN2MAPTALDH1A1ALOX5PTGS2 | |
| SCHEMBL28981975 | 0.76 | IMPDH2 (0.45) | MAPTTSHRCNR2 | |
| SCHEMBL31287474 | 0.75 | TOP1 (0.52) | SMN1; SMN2MAPTALDH1A1ALOX5PTGS2 | |
| SCHEMBL11357537 | 0.74 | LTA4H (0.41) | MAPT | |
| SCHEMBL28309046 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1ALOX5PTGS2 | |
| SCHEMBL1613739 | 0.74 | TOP1 (0.53) | SMN1; SMN2MAPTALDH1A1ALOX5PTGS2 | |
| SCHEMBL9835141 | 0.74 | PPARG (0.42) | MAPTALDH1A1KDM4EALOX15HSD17B10 | |
| SCHEMBL734007 | 0.73 | ALDH1A1 (0.43) | SMN1; SMN2MAPTALDH1A1ALOX5KDM4E | |
| SCHEMBL7467421 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1ALOX5PTGS2 | |
| SCHEMBL24663171 | 0.72 | ALDH1A1 (0.45) | SMN1; SMN2MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |