Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338656 | 0.79 | CYP11B2 (0.36) | CDC7CYP11B1CYP11B2PKN2 | |
| SCHEMBL7346574 | 0.77 | KDM4E (0.39) | CDC7CYP11B1CYP11B2PKN2 | |
| SCHEMBL7341653 | 0.77 | PKN2 (0.32) | CDC7CYP11B1CYP11B2PKN2 | |
| SCHEMBL11072613 | 0.70 | MEN1 (0.37) | PIM1 | |
| SCHEMBL7346248 | 0.68 | SIRT3 (0.41) | CDC7CYP11B2 | |
| SCHEMBL7347683 | 0.66 | KDM4E (0.43) | CDC7CYP11B2PKN2 | |
| SCHEMBL7342355 | 0.65 | CES1 (0.40) | — | |
| SCHEMBL11077780 | 0.65 | CSNK1A1 (0.32) | — | |
| SCHEMBL12210308 | 0.65 | MAOA (0.39) | CDC7PIM1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7337010 | 0.64 | CES1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474786-A | CONGESTIVE HEART FAILURE | SCHERING CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0102046-A1 | Tricyclic lactams, method for making them, pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |