Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286087 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTNOS1GAAMAPK1 | |
| SCHEMBL27872987 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTNOS1GAAMAPK1 | |
| SCHEMBL11439559 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTNOS1GAAMAPK1 | |
| SCHEMBL4611628 | 0.75 | NOS1 (0.41) | ALDH1A1MAPTNOS1GAAMAPK1 | |
| SCHEMBL2173488 | 0.74 | — | — | |
| SCHEMBL27706914 | 0.70 | RAB9A (0.48) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL276275 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MAPTGAAMAPK1NPC1 | |
| SCHEMBL3774987 | 0.69 | CYP3A4 (0.48) | ALDH1A1MAPTGAAMAPK1NPC1 | |
| SCHEMBL25916551 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTNOS1GAAMAPK1 | |
| SCHEMBL27655003 | 0.68 | NOS1 (0.45) | ALDH1A1MAPTNOS1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008627-B1 | QUINAZOLINE DERIVATIVES, AZO DYES DERIVED FROM THE QUINAZOLINES AND THEIR USE AS PIGMENTS | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |
| EP-0008627-A2 | Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |