Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968222 | 0.77 | SMN1; SMN2 (0.60) | NPC1RAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL9614627 | 0.75 | HSD17B3 (0.44) | NPC1RAB9APOLBSMN1; SMN2LMNA | |
| 1-Allyloxy-4-Butoxybenzene SCHEMBL3390966 | 0.74 | LTA4H (0.52) | NPC1RAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7279376 | 0.73 | CYP3A4 (0.47) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL8595624 | 0.73 | POLB (0.43) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL817611 | 0.73 | NPC1 (0.59) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL31343324 | 0.72 | ALDH1A1 (0.47) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11887705 | 0.72 | ALOX5 (0.49) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL7227214 | 0.71 | NPC1 (0.44) | NPC1RAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL28337675 | 0.71 | KMT2A (0.47) | NPC1RAB9APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435397-A | ADRENERGIC BLOCKING AGENTS, 4-(3-ARYLOXY-2-HYDROXYPROPYL) SUBSTITUTED | NIPPON SHINYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |