Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670325 | 0.87 | MAPT (0.46) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL16682152 | 0.81 | PAX8 (0.42) | SMN1; SMN2POLBMAPTALDH1A1NPC1 | |
| SCHEMBL3832407 | 0.80 | ALDH1A1 (0.77) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL11075339 | 0.77 | NPC1 (0.43) | SMN1; SMN2POLBMAPTLMNANPC1 | |
| SCHEMBL6783648 | 0.77 | POLB (0.64) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL1092083 | 0.76 | L3MBTL1 (0.61) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL5049713 | 0.76 | LMNA (0.52) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL2537514 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL14756119 | 0.75 | SMN1; SMN2 (0.77) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL28573186 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527816-A | AGRICULTURAL USE | ROHM AND HAAS COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0529974-A1 | Fungicidal 2-aryl-2-cyano-2-(aryloxyalkyl)ethyl-1,2,4-triazoles | ROHM AND HAAS COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |