Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | CTSV | O60911 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067298 | 0.86 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BCTSV | |
| SCHEMBL11068410 | 0.85 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BCTSV | |
| SCHEMBL31091843 | 0.82 | PTGES (0.48) | CTSVCTSLMEN1KMT2AMAPT | |
| SCHEMBL5241194 | 0.82 | MAPT (0.48) | HTR1AADRA1DADRA1AADRA1BCTSV | |
| SCHEMBL13851053 | 0.81 | LMNA (0.50) | HTR1AADRA1DADRA1AADRA1BCTSV | |
| SCHEMBL2088203 | 0.80 | TUBB4A (0.49) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL1944404 | 0.80 | POLB (0.46) | HTR1AADRA1DADRA1AADRA1BCTSV | |
| SCHEMBL30501940 | 0.80 | POLB (0.46) | HTR1AADRA1DADRA1AADRA1BCTSV | |
| SCHEMBL21071296 | 0.80 | HTR1A (0.55) | HTR1AADRA1DADRA1AADRA1BCTSV | |
| SCHEMBL16427372 | 0.80 | MEN1 (0.55) | HTR1AADRA1DADRA1AADRA1BCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |