Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734940 | 0.86 | VCAM1 (0.50) | VCAM1GPR35MAOAMAOBGRIN2D | |
| SCHEMBL11727517 | 0.86 | VCAM1 (0.53) | VCAM1GPR35MAOAMAOBGRIN2D | |
| SCHEMBL3643976 | 0.84 | VCAM1 (0.47) | VCAM1GPR35MAOAMAOBGRIN2D | |
| SCHEMBL11062636 | 0.84 | VCAM1 (0.47) | VCAM1GPR35MAOAMAOBGRIN2D | |
| SCHEMBL12261039 | 0.84 | VCAM1 (0.47) | VCAM1GPR35MAOAMAOBGRIN2D | |
| SCHEMBL1736238 | 0.79 | GPR35 (0.59) | VCAM1GPR35MAOAMAOBGRIN2D | |
| Nitroxinil SCHEMBL166956 | 0.79 | TTR (0.60) | VCAM1GPR35MAOAMAOBGRIN2D | |
| Nitroxinil SCHEMBL31425481 | 0.79 | TTR (0.60) | VCAM1GPR35MAOAMAOBGRIN2D | |
| SCHEMBL4167481 | 0.78 | VCAM1 (0.59) | VCAM1GPR35MAOAMAOBGRIN2D | |
| SCHEMBL11067720 | 0.77 | GPR35 (0.61) | GPR35TTRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |