Nitroxinil

Nitroxinil

SCHEMBL166956

N#Cc1cc(I)c(O)c([N+](=O)[O-])c1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.60
ALB P02768 1/20 0.60
VCAM1 P19320 3/20 0.56
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
GRIN3A Q8TCU5 1/20 0.45
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
CTSB P07858 1/20 0.43
GPR35 Q9HC97 4/20 0.43
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitroxinil SCHEMBL31425481 1.00 TTR (0.60) TTRALBVCAM1MEN1KMT2A
Nitroxinil SCHEMBL8731613 0.92 MEN1 (0.62) TTRALBVCAM1MEN1KMT2A
SCHEMBL4167481 0.82 VCAM1 (0.59) TTRVCAM1MEN1KMT2AGRIN2D
Phenanthroline SCHEMBL21326165 0.82 MEN1 (0.54) TTRALBMEN1KMT2ALMNA
SCHEMBL28490634 0.81 VCAM1 (0.58) TTRVCAM1MEN1KMT2AGRIN2D
Ioxynil SCHEMBL28170997 0.81 TTR (0.53) TTRALBVCAM1MEN1KMT2A
SCHEMBL9899661 0.79 VCAM1 (0.56) TTRVCAM1MEN1KMT2ALMNA
SCHEMBL1736238 0.79 GPR35 (0.59) TTRALBVCAM1MEN1KMT2A
SCHEMBL1735159 0.79 MEN1 (0.60) TTRALBVCAM1MEN1KMT2A
SCHEMBL1736320 0.79 VCAM1 (0.51) TTRVCAM1MEN1KMT2AGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1997 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4586826-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL In the Bowl Animal Health, Inc. (US) 2025-07-23 EP claimed
WO-2024059837-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL IN THE BOWL ANIMAL HEALTH, INC. (US) 2024-03-21 WO claimed
EP-4160211-A1 DETECTING THE EXPOSURE OF A SUBJECT TO A THYROID DISRUPTING CHEMICAL, EVEN BEFORE HYPOTHYROIDISM APPEARS Moreno Navarro, José Carlos (ES) 2023-04-05 EP claimed
US-20220323472-A1 ANTI-PARASITIC COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES SPALLITTA FRANK ANTHONY (US) 2022-10-13 US claimed
WO-2022212399-A1 ANTI-PARASITIC COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES SPALLITTA FRANK ANTHONY (US) 2022-10-06 WO claimed
US-20170135347-A1 INSECTICIDAL, MITICIDAL, NEMATICIDAL, MOLLUSCICIDAL, MICROBICIDAL, OR BACTERICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-05-18 US claimed
CN-106659160-A Insecticide, miticide, nematicide, molluscicide, disinfectant, or bactericide composition, and pest control method 日产化学工业株式会社 2017-05-10 CN claimed
CN-105748457-A A nitroxynil injection for veterinary use and a preparing method thereof 重庆布尔动物药业有限公司 2016-07-13 CN claimed
WO-2016018937-A1 COMPOSITIONS AND METHODS FOR CONTROLLING INSECT PROLIFERATION THE JOHNS HOPKINS UNIVERSITY (US) 2016-02-04 WO claimed
EP-2875726-A1 Novel uses of veterinary compositions for anti-parasitic treatment Ceva Animal Health (US) 2015-05-27 EP claimed
WO-2004039172-A1 ORAL VETERINARY DRUG DELIVERY SYSTEM AND/OR FEED ADDITIVE DELIVERY SYSTEM, PROCESS FOR THE PREPARATION AND USE THEREOF SZOKE ANNAMARIA (HU) 2004-05-13 WO claimed
EP-0710105-B1 SYNERGISTIC ANTHELMINTIC COMPOSITIONS AGAINST FASCIOLA HEPATICA AND OTHER FASCIOLA SPECIES UNIV AUSTRALIAN (AU) 2003-07-30 EP claimed
EP-0710105-A4 SYNERGISTIC ANTHELMINTIC COMPOSITIONS UNIV AUSTRALIAN (AU) 1998-06-10 EP claimed
EP-0710105-A1 SYNERGISTIC ANTHELMINTIC COMPOSITIONS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1996-05-08 EP claimed
WO-1994028887-A1 SYNERGISTIC ANTHELMINTIC COMPOSITIONS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1994-12-22 WO claimed
US-4957494-A Multi-layer delivery system ALZA CORPORATION (US) 1990-09-18 US claimed
US-4874388-A Multi-layer delivery system ALZA CORPORATION (US) 1989-10-17 US claimed
US-4643893-A FOR ADMINISTERING MEDICINE TO ANIMAL RUMEN C.R.B. VIRBAC S.A. (FR) 1987-02-17 US claimed
US-4228149-A Sustained release compositions BEECHAM GROUP LIMITED (GB) 1980-10-14 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220323472-A1 ANTI-PARASITIC COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES CTSA, DDT, CTSV TTR 158/4885ALB 1147/4885VCAM1 1926/4885
US-20170135347-A1 INSECTICIDAL, MITICIDAL, NEMATICIDAL, MOLLUSCICIDAL, MICROBICIDAL, OR BACTERICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST DDT, ACHE, DRD5 TTR 4052/4885ALB 3904/4885VCAM1 4819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.