Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720372 | 0.84 | HSPD1 (0.40) | ALOX5MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL10904085 | 0.80 | TDP1 (0.44) | MEN1KMT2ASMN1; SMN2TDP1CA2 | |
| SCHEMBL9466971 | 0.79 | KCNA5 (0.46) | KMT2ASMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL11067677 | 0.75 | TDP1 (0.35) | MEN1KMT2AGAATDP1CA2 | |
| SCHEMBL22548161 | 0.74 | CA2 (0.43) | MEN1KMT2AGAATDP1CA2 | |
| SCHEMBL11075772 | 0.73 | MEN1 (0.38) | MEN1KMT2AGAASMN1; SMN2TDP1 | |
| SCHEMBL6115966 | 0.72 | CA2 (0.44) | MEN1KMT2ATDP1CA2CA1 | |
| SCHEMBL10904098 | 0.71 | POLB (0.49) | MEN1KMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL10906610 | 0.70 | MEN1 (0.43) | MEN1KMT2ACA2CA1HPGD | |
| SCHEMBL10907962 | 0.70 | MEN1 (0.43) | MEN1KMT2ACA2CA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479003-A | Heterocyclic-hydroxy-substituted carboxylate esters | PHILIP MORRIS, INCORPORATED (US) | 1984-10-23 | — | — | US | disclosed |
| US-4312368-A | Smoking compositions | PHILIP MORRIS, INCORPORATED (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0037163-A2 | Flavouring agents, smoking compositions, combustible articles and foodstuffs containing such agents, and a method of producing the same | PHILIP MORRIS INCORPORATED (US) | 1981-10-07 | — | — | EP | disclosed |