Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720368 | 0.84 | DPP8 (0.36) | MEN1KMT2ANPC1DPP8DPP9 | |
| SCHEMBL11068158 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL10904084 | 0.78 | POLB (0.43) | MEN1KMT2ASMN1; SMN2NPC1TSHR | |
| SCHEMBL9466966 | 0.78 | CYP3A4 (0.41) | MEN1KMT2ASMN1; SMN2NPC1TSHR | |
| SCHEMBL11075778 | 0.73 | ALOX5 (0.38) | MEN1GAAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8327638 | 0.68 | PIN1 (0.41) | MEN1GAAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL22092656 | 0.68 | LMNA (0.44) | MEN1GAAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL12238625 | 0.66 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL26833445 | 0.66 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL26833401 | 0.66 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479003-A | Heterocyclic-hydroxy-substituted carboxylate esters | PHILIP MORRIS, INCORPORATED (US) | 1984-10-23 | — | — | US | disclosed |
| US-4312368-A | Smoking compositions | PHILIP MORRIS, INCORPORATED (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0037163-A2 | Flavouring agents, smoking compositions, combustible articles and foodstuffs containing such agents, and a method of producing the same | PHILIP MORRIS INCORPORATED (US) | 1981-10-07 | — | — | EP | disclosed |