Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069577 | 0.96 | SIRT1 (0.52) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL1063544 | 0.88 | SIRT1 (0.68) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL9122584 | 0.85 | PDE1A (0.63) | — | |
| SCHEMBL10856971 | 0.82 | SIRT1 (0.61) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL10859893 | 0.82 | SIRT1 (0.61) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL9430619 | 0.82 | ADORA2A (0.61) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL9430131 | 0.81 | ADORA2A (0.56) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL11286152 | 0.80 | PDE2A (0.59) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL9430769 | 0.80 | ADORA2A (0.55) | SIRT1SIRT3SIRT5ADORA1ADORA2A | |
| SCHEMBL7918903 | 0.79 | ADORA1 (0.57) | SIRT1SIRT3SIRT5ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469698-A | SEDATIVES, TRANQUILIZERS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-09-04 | — | — | US | claimed |